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Machu Picchu, Galapagos, Patagonia, Iguazu Falls & More

Peru Machu Picchu
Peru Machu Picchu
Peru Machu Picchu
Peru Machu Picchu

Premier Multi-Country South America Trips

Choose from our most popular suggested itineraries below and then give us a call to discuss your custom travel plans with a specialist.

Many of our travelers want to combine different countries within South America. Popular combinations include Peru/Ecuador (including the Galapagos Islands), Argentina/Chile (including Patagonia on both sides of the border, by land or sea), and Argentina/Brazil (combining Buenos Aires, Iguazu Falls, and Rio de Janeiro).

Multi Country Journey

The South American Grand Tour, Reimagined

An epic one-month journey

Visit the highlights of Latin America on this voyage through Ecuador and the Galapagos Islands, Peru, Chile, Argentina, and Brazil.


31 Days, flexible start dates from $17,500 / person with 2 travelers

Brazil Argentina HAB THUMB

Highlights of Brazil & Argentina

Combine Buenos Aires, Patagonia, Iguazu Falls & Rio de Janeiro

See some of the best of South America on this trip, starting in the Argentine capital. You then take in the natural wonders of Patagonia and Iguazu Falls, followed by 3 days in the tropical metropolis of Rio.


12 Days, flexible start dates $4,450 / person with 2 travelers

Argentina Chile Patagonia

Highlights of Chilean & Argentine Patagonia

If you have 2 weeks, this itinerary is tough to beat

You can start in Santiago or in Buenos Aires, seeing both of these capital cities, along with a full exploration of the most magnificent sites in Patagonia on both sides of the border.


14 Days, flexible start dates $7,070 / person with 4 travelers

Iguazu Falls

Amazon, Machu Picchu, Iguazu Falls & Rio de Janeiro

The Amazon Jungle, Cusco, Machu Picchu, Iguazu Falls & Rio

Four of the highlights of South America in one trip. Stay in a premier Amazon eco-lodge, then explore Cusco and Machu Picchu before traveling to Iguazu Falls, and finish your trip in glittering Rio de Janeiro.


15 days, flexible start dates $6,570 / person with 2 travelers

Mendoza  banner

Chile & Argentina Wine & Culinary Adventure

South America's top wine-producing regions

Experience the best of South American wine production. Lots of local wineries and tastings, cultural highlights, and historic cities.


10 days, flexible start dates $6,190 / person with 2 travelers

Why Travel With Vaya to South America

We are specialists in this area of the world and our focus and exacting standards mean that our trips are truly exceptional. We have first hand, deep knowledge of each of our destinations, and we bring that knowledge plus a refined sensibility to bear on our multi-country South America itineraries. In all locations, you’ll experience our hallmark premier small hotels, top quality private guides, and outstanding excursions. Our most popular multi-country trips tie together different combinations of Peru, the Galapagos Islands, and Patagonia (southern Argentina & Chile).

In Peru, you’ll enjoy the finest local hotels, carefully chosen to reflect the best of what the country has to offer, whether you prefer a simple B&B style inn, a boutique hotel, an exceptional jungle lodge, or some combination of all of the above.

In the Galapagos, you’ll be on one of the finest small vessels available. From firsthand experience, we carefully choose our vessels from among the dozens of options available. Our criteria are simple: we only want to offer the highest quality ships, guides, and itineraries, as well as the best value in any vessel class.

Our trips to Patagonia will help you get to know this remote region up close. There is a lot to see in Patagonia, and our itineraries are designed to maximize your time and your access to the best hiking trails in the region. Our most popular Patagonia itineraries combine the highlights on both sides of the Argentina/Chile border, with seamless logistics.

You can review the suggested itineraries above to get a sense of some of the options you have. We are happy to speak with you about the details and help you figure out how to make the most of your time and budget. Please call us to discuss your plans.